Remote USA

Principal Database (Medidata Rave) Programmer Contractor

For Contract Roles Only:
Job Description:
  • Provide training and mentoring to (Senior) Database Programmers related to CDMS systems and processes to be performed by Database Programmers
  • Plan client deliverables and manage project budgets
  • Act as programming lead for a study/ program
  • Setup of study databases and ePRO/ IRT (if applicable) based on provided specifications (e.g. dummy CRF pages, study design specification, URS)
  • May write or review the Database Validation Plan
  • Perform database validation/ UAT in collaboration with CDM
  • May review Data Validation Plan (DVP) with regards to feasibility of checks in CDMS
  • Program edit checks within CDM systems and/ or SAS according to data validation plan
  • May write or support CDM with creation of edit check test plan
  • May perform or support CDM with import and export of data
  • May write or support CDM with creation of data transfer specifications including liaising with vendors to facilitate connections between CDMS and other systems
  • May perform or support CDM with validation of Data transfer programming
  • Create and manage users incl. access rights (if applicable)
  • Provide helpdesk for users in EDC studies
  • Perform the execution of the database lock in collaboration with CDM
  • File/ archive essential documents
  • Responsible to escalate any issues on projects or the need for potential SOP deviations
  • Perform system validation, create test scripts for system validation as well as perform UAT
  • Actively contribute to the organization and development of processes to enhance the work (e.g. writing/ review of SOPs including related documents and perform training)
  • Provide input into proposals which include Data Management and may attend Bid Defense meetings Depending on level of qualification
  • Perform SAS programming related to data management outputs (e.g. data review listing, clean patient tracker, SAE reconciliation listing, ad-hoc reports)
  • Develop and validate global SAS macros for data management processes
  • Program/validate SDTM datasets incl. define.XML and SDTM reviewer’s guide
  • Provide training and mentoring related to SAS programming
Required / Preferred Experience, skills, and qualifications:
  • Bachelor’s Degree, preferably in life science, computer science or equivalent
  • Minimum of 8 years relevant database programming experience in pharmaceutical or CRO industry, including 5 years as Senior Database Programmer (Medidata Rave)
  • Familiarity with different CDMS systems and industry standards applicable for programming in GxP environment (e.g. 21 CFR part 11, GAMP)
  • Ability to handle multiple tasks to meet deadlines
  • Proven leadership skills
  • Excellent verbal and communication skills
  • Ability to deal effectively with sponsors and internal customers
  • Ability and willingness to travel on occasion
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